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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4311
Target Type SINGLE PROTEIN
Preferred Name Serine/threonine-protein kinase PAK6
Synonyms PAK-5 | PAK-6 | PAK5 | PAK6 | Serine/threonine-protein kinase PAK 6 | p21-activated kinase 6
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > ste protein kinase group > ste protein kinase ste20 family > ste protein kinase pakb subfamily

Target Components

Component Description Relationship Accession
Serine/threonine-protein kinase PAK 6 SINGLE PROTEIN Q9NQU5

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000137843
Ensembl ENSG00000137843
GO Molecular Function GO:0004674 (protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO Biological Process GO:0006468 (protein phosphorylation)
Wikipedia PAK6

Target Cross References - Protein

canSAR Q9NQU5
Human Protein Atlas ENSG00000137843
IntAct Q9NQU5
Guide to Pharmacology 2137 (p21 protein (Cdc42/Rac)-activated kinase 6)
PharmGKB PA32921
Reactome REACT_18266 (Axon guidance.)
UniProt Q9NQU5

Target Cross References - Domain

InterPro IPR000095 (PAK_box_Rho-bd.)
IPR000719 (Prot_kinase_cat_dom.)
IPR002290 (Ser/Thr_prot_kinase_dom.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017442 (Se/Thr_prot_kinase-like_dom.)
Pfam PF00069 (Pkinase)
PF00786 (PBD)

Target Cross References - Structure

PDBe 2C30 2ODB
CREDO 2C30 2ODB
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