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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4306
Target Type SINGLE PROTEIN
Preferred Name Voltage-gated potassium channel subunit Kv1.5
Synonyms HPCN1 | KCNA5 | Potassium voltage-gated channel subfamily A member 5 | Voltage-gated potassium channel HK2 | Voltage-gated potassium channel subunit Kv1.5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > potassium channels > voltage-gated potassium channel

Target Components

Component Description Relationship Accession
Potassium voltage-gated channel subfamily A member 5 SINGLE PROTEIN P22460

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2362996 Voltage-gated potassium channel PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000130037
Ensembl ENSG00000130037
GO Cellular Component GO:0005794 (Golgi apparatus)
GO:0008076 (voltage-gated potassium channel complex)
GO Molecular Function GO:0005251 (delayed rectifier potassium channel activity)
Wikipedia KCNA5

Target Cross References - Protein

canSAR P22460
CGD Atrial fibrillation, familial, 7
Human Protein Atlas ENSG00000130037
Guide to Pharmacology 542 (Kv1.5)
PharmGKB PA208
UniProt P22460 Q4KKT8 Q4VAJ1 Q4VAJ2 Q9UDA4

Target Cross References - Domain

InterPro IPR000210 (BTB/POZ-like.)
IPR003091 (K_chnl.)
IPR003131 (K_chnl_volt-dep_Kv_tetra.)
IPR003968 (K_chnl_volt-dep_Kv.)
IPR003972 (K_chnl_volt-dep_Kv1.)
IPR004052 (K_chnl_volt-dep_Kv1.5.)
IPR005821 (Ion_trans.)
IPR011333 (BTB/POZ_fold.)
Pfam PF00520 (Ion_trans)
PF02214 (K_tetra)
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