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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4296
Preferred Name Sodium channel protein type IX alpha subunit
Synonyms NENA | Neuroendocrine sodium channel | PN1 | Peripheral sodium channel 1 | SCN9A | Sodium channel protein type 9 subunit alpha | Sodium channel protein type IX subunit alpha | Voltage-gated sodium channel subunit alpha Nav1.7 | hNE-Na
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > voltage-gated sodium channel

Target Components

Component Description Relationship Accession
Sodium channel protein type 9 subunit alpha SINGLE PROTEIN Q15858

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2331043 Sodium channel alpha subunit PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000169432
Ensembl ENSG00000169432
GO Cellular Component GO:0001518 (voltage-gated sodium channel complex)
GO Molecular Function GO:0005248 (voltage-gated sodium channel activity)
Wikipedia Nav1.7

Target Cross References - Protein

CGD Paroxysmal extreme pain disorder
Human Protein Atlas ENSG00000169432
Guide to Pharmacology 584 (Nav1.7)
PharmGKB PA35010
Reactome REACT_18266 (Axon guidance.)
UniProt A1BUH5 Q15858 Q6B4R9 Q6B4S0 Q6B4S1 Q70HX1 Q70HX2 Q8WTU1 Q8WWN4

Target Cross References - Domain

InterPro IPR000048 (IQ_motif_EF-hand-BS.)
IPR001696 (Na_channel_asu.)
IPR005821 (Ion_trans.)
IPR010526 (Na_trans_assoc.)
Pfam PF00520 (Ion_trans)
PF06512 (Na_trans_assoc)