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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4183
Target Type SINGLE PROTEIN
Preferred Name P-selectin glycoprotein ligand 1
Synonyms CD_antigen=CD162 | P-selectin glycoprotein ligand 1 | PSGL-1 | SELPLG | Selectin P ligand
Organism Homo sapiens
Species Group No
Protein Target Classification
  • adhesion

Target Components

Component Description Relationship Accession
P-selectin glycoprotein ligand 1 SINGLE PROTEIN Q14242

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3301394 P-selectin/P-selectin glycoprotein ligand 1 PROTEIN-PROTEIN INTERACTION

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000110876
Ensembl ENSG00000110876
GO Cellular Component GO:0001931 (uropod)
GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0001618 (virus receptor activity)
GO:0005102 (receptor binding)
GO:0005515 (protein binding)
GO Biological Process GO:0007155 (cell adhesion)
GO:0016032 (viral process)
GO:0046718 (viral entry into host cell)
GO:0050900 (leukocyte migration)
GO:0050902 (leukocyte adhesive activation)
GO:0071354 (cellular response to interleukin-6)
Wikipedia P-selectin_glycoprotein_ligand-1

Target Cross References - Protein

canSAR Q14242
Human Protein Atlas ENSG00000110876
IntAct Q14242
Open Targets ENSG00000110876
PharmGKB PA35644
Reactome R-HSA-202733 (Cell surface interactions at the vascular wall.)
UniProt A8K2Y0 B4DQC3 B7Z5C7 J3KMX6 Q12775 Q14242 Q6GTW7 Q8N7J7

Target Cross References - Structure

PDBe 1G1S
CREDO 1G1S
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