ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL4071
Target Type SINGLE PROTEIN
Preferred Name Cathepsin G
Synonyms CG | CTSG | Cathepsin G
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease > serine protease pa clan > serine protease s1a subfamily

Target Components

Component Description Relationship Accession
Cathepsin G SINGLE PROTEIN P08311

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000100448
Ensembl ENSG00000100448
GO Cellular Component GO:0005615 (extracellular space)
GO:0005886 (plasma membrane)
GO:0009986 (cell surface)
GO:0030141 (stored secretory granule)
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO:0008201 (heparin binding)
GO Biological Process GO:0006508 (proteolysis)
GO:0006955 (immune response)
Wikipedia Cathepsin_G

Target Cross References - Protein

canSAR P08311
Human Protein Atlas ENSG00000100448
Guide to Pharmacology 2348 (cathepsin G)
PharmGKB PA27032
Reactome REACT_15380 (Diabetes pathways.)
UniProt P08311 Q6IBJ6 Q9UCA5 Q9UCU6

Target Cross References - Domain

InterPro IPR001254 (Peptidase_S1_S6.)
IPR001314 (Peptidase_S1A.)
IPR009003 (Pept_cys/ser_Trypsin-like.)
IPR018114 (Peptidase_S1/S6_AS.)
Pfam PF00089 (Trypsin)

Target Cross References - Structure

PDBe 1AU8 1CGH 1KYN 1T32
CREDO 1AU8 1CGH 1KYN 1T32
spacer
spacer