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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL4004
Preferred Name Phosphorylase kinase gamma subunit 1
Synonyms PHK-gamma-M | PHKG | PHKG1 | Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform | Phosphorylase kinase subunit gamma-1 | Serine/threonine-protein kinase PHKG1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase phk family

Target Components

Component Description Relationship Accession
Phosphorylase b kinase gamma catalytic chain, skeletal muscle/heart isoform SINGLE PROTEIN Q16816

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2111324 Phosphorylase kinase PROTEIN COMPLEX GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000164776
Ensembl ENSG00000164776
GO Cellular Component GO:0005829 (cytosol)
GO:0005964 (phosphorylase kinase complex)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004689 (phosphorylase kinase activity)
GO:0005516 (calmodulin binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0019899 (enzyme binding)
GO:0050321 (tau-protein kinase activity)
GO Biological Process GO:0005975 (carbohydrate metabolic process)
GO:0005977 (glycogen metabolic process)
GO:0005978 (glycogen biosynthetic process)
GO:0005980 (glycogen catabolic process)
GO:0006468 (protein phosphorylation)
GO:0016310 (phosphorylation)
Wikipedia PHKG1

Target Cross References - Protein

canSAR Q16816
Human Protein Atlas ENSG00000164776
Guide to Pharmacology 2145
Open Targets ENSG00000164776
PharmGKB PA33271
Pharos Q16816 (Tchem)
Reactome R-HSA-70221 (Glycogen breakdown (glycogenolysis).)
UniProt B7Z1D0 F5H2S1 Q16816 Q75LP5

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR002291 (Phosph_kin_gamma.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR020636 (Ca/CaM-dep_Ca-dep_prot_Kinase.)
Pfam PF00069 (Pkinase)