ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3969
Target Type SINGLE PROTEIN
Preferred Name Carbonic anhydrase VB
Synonyms CA-VB | CA5B | Carbonate dehydratase VB | Carbonic anhydrase 5B, mitochondrial | Carbonic anhydrase VB
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > lyase

Target Components

Component Description Relationship Accession
Carbonic anhydrase 5B, mitochondrial SINGLE PROTEIN Q9Y2D0

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095180 Carbonic anhydrase PROTEIN FAMILY
CHEMBL2111457 Carbonic anhydrase V PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000169239
Ensembl ENSG00000169239
GO Cellular Component GO:0005739 (mitochondrion)
GO:0005759 (mitochondrial matrix)
GO Molecular Function GO:0004089 (carbonate dehydratase activity)
GO:0008270 (zinc ion binding)
GO:0016829 (lyase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006730 (one-carbon metabolic process)
GO:0015701 (bicarbonate transport)
Wikipedia CA5B

Target Cross References - Protein

canSAR Q9Y2D0
Human Protein Atlas ENSG00000169239
Open Targets ENSG00000169239
PharmGKB PA25993
Reactome R-HSA-1475029 (Reversible hydration of carbon dioxide.)
UniProt A8K4T5 Q9Y2D0

Target Cross References - Domain

InterPro IPR001148 (Carbonic_anhydrase_a.)
IPR018338 (Carbonic_anhydrase_a-class_CS.)
IPR018437 (CA-VB_mt.)
IPR023561 (Carbonic_anhydrase_a-class.)
Pfam PF00194 (Carb_anhydrase)
spacer
spacer