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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3674
Target Type SINGLE PROTEIN
Preferred Name Fatty acid binding protein epidermal
Synonyms E-FABP | Epidermal-type fatty acid-binding protein | FABP5 | Fatty acid-binding protein 5 | Fatty acid-binding protein, epidermal | PA-FABP | Psoriasis-associated fatty acid-binding protein homolog
Organism Homo sapiens
Species Group No
Protein Target Classification
  • auxiliary transport protein > fatty acid binding protein family

Target Components

Component Description Relationship Accession
Fatty acid-binding protein, epidermal SINGLE PROTEIN Q01469

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000164687
Ensembl ENSG00000164687
GO Cellular Component GO:0005654 (nucleoplasm)
GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0005215 (transporter activity)
GO:0005504 (fatty acid binding)
GO:0005515 (protein binding)
GO:0008289 (lipid binding)
GO Biological Process GO:0006006 (glucose metabolic process)
GO:0006629 (lipid metabolic process)
GO:0006656 (phosphatidylcholine biosynthetic process)
GO:0006810 (transport)
GO:0008544 (epidermis development)
GO:0009611 (response to wounding)
GO:0015758 (glucose transport)
GO:0019433 (triglyceride catabolic process)
Wikipedia FABP5

Target Cross References - Protein

canSAR Q01469
Human Protein Atlas ENSG00000164687
IntAct Q01469
Guide to Pharmacology 2535
Open Targets ENSG00000164687
PharmGKB PA27961
Reactome R-HSA-163560 (Hormone-sensitive lipase (HSL)-mediated triacylglycerol hydrolysis.)
R-HSA-5362517 (Signaling by Retinoic Acid.)
R-HSA-6798695 (Neutrophil degranulation.)
UniProt B2R4K0 Q01469

Target Cross References - Domain

InterPro IPR000463 (Fatty_acid-bd.)
IPR000566 (Lipocln_cytosolic_FA-bd_dom.)
IPR011038 (Calycin-like.)
IPR012674 (Calycin.)
IPR031259 (iLBP.)
Pfam PF00061 (Lipocalin)

Target Cross References - Structure

PDBe 1B56 4AZM 4AZR 4LKP 4LKT 5HZ5
CREDO 1B56 4AZM 4AZR 4LKP 4LKT 5HZ5
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