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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3629
Target Type SINGLE PROTEIN
Preferred Name Casein kinase II alpha
Synonyms CK II alpha | CK2A1 | CSNK2A1 | Casein kinase II subunit alpha
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > other protein kinase group > other protein kinase ck2 family

Target Components

Component Description Relationship Accession
Casein kinase II subunit alpha SINGLE PROTEIN P68400

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3038477 Casein kinase II alpha/beta PROTEIN COMPLEX
CHEMBL2095191 Casein kinase II PROTEIN COMPLEX GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000101266
Ensembl ENSG00000101266
GO Cellular Component GO:0005829 (cytosol)
GO:0005886 (plasma membrane)
GO:0016580 (Sin3 complex)
GO:0016581 (NuRD complex)
GO Molecular Function GO:0004674 (protein serine/threonine kinase activity)
GO:0005524 (ATP binding)
GO:0047485 (protein N-terminus binding)
GO Biological Process GO:0007411 (axon guidance)
GO:0016055 (Wnt receptor signaling pathway)
Wikipedia Casein_kinase_2,_alpha_1

Target Cross References - Protein

canSAR P68400
Human Protein Atlas ENSG00000101266
IntAct P68400
PharmGKB PA26957
Reactome REACT_18266 (Axon guidance.)
UniProt B4DYS6 D3DVV8 P19138 P20426 P68400 Q14013 Q5U065

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_cat_dom.)
IPR002290 (Ser/Thr_prot_kinase_dom.)
IPR008271 (Ser/Thr_prot_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017442 (Se/Thr_prot_kinase-like_dom.)
Pfam PF00069 (Pkinase)

Target Cross References - Structure

PDBe 1JWH 1NA7 1PJK 2PVR 2ZJW 3BQC 3C13 3FWQ 3H30 3JUH 3MB6 3MB7 3NGA 3NSZ 3PE4
CREDO 1JWH 1NA7 1PJK 2PVR 2ZJW 3BQC 3C13 3FWQ 3H30 3JUH 3MB6 3MB7 3NGA 3NSZ 3PE4
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