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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3591
Target Type SINGLE PROTEIN
Preferred Name GABA receptor delta subunit
Synonyms GABA(A) receptor subunit delta | GABRD | Gamma-aminobutyric acid receptor subunit delta
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > ligand-gated ion channel > gaba-a receptor

Target Components

Component Description Relationship Accession
Gamma-aminobutyric acid receptor subunit delta SINGLE PROTEIN O14764

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2093872 GABA-A receptor; anion channel PROTEIN COMPLEX GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000187730
Ensembl ENSG00000187730
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0030054 (cell junction)
GO:0034707 (chloride channel complex)
GO:0045202 (synapse)
GO:0045211 (postsynaptic membrane)
GO:1902711 (GABA-A receptor complex)
GO Molecular Function GO:0004890 (GABA-A receptor activity)
GO:0005230 (extracellular ligand-gated ion channel activity)
GO:0005254 (chloride channel activity)
GO:0005515 (protein binding)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006821 (chloride transport)
GO:0007165 (signal transduction)
GO:0007268 (chemical synaptic transmission)
GO:0034220 (ion transmembrane transport)
GO:1902476 (chloride transmembrane transport)
Wikipedia GABRD

Target Cross References - Protein

canSAR O14764
Human Protein Atlas ENSG00000187730
IntAct O14764
Open Targets ENSG00000187730
PharmGKB PA28498
Pharos O14764 (Tclin)
UniProt O14764 Q8N4N9

Target Cross References - Domain

InterPro IPR006028 (GABAA/Glycine_rcpt.)
IPR006029 (Neurotrans-gated_channel_TM.)
IPR006201 (Neur_channel.)
IPR006202 (Neur_chan_lig-bd.)
IPR008098 (GABAAd_rcpt.)
IPR018000 (Neurotransmitter_ion_chnl_CS.)
Pfam PF02931 (Neur_chan_LBD)
PF02932 (Neur_chan_memb)
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