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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3578
Target Type SINGLE PROTEIN
Preferred Name Aldehyde dehydrogenase dimeric NADP-preferring
Synonyms ALDH3 | ALDH3A1 | ALDHIII | Aldehyde dehydrogenase 3 | Aldehyde dehydrogenase family 3 member A1 | Aldehyde dehydrogenase, dimeric NADP-preferring
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Aldehyde dehydrogenase, dimeric NADP-preferring SINGLE PROTEIN P30838

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000108602
Ensembl ENSG00000108602
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005829 (cytosol)
GO Molecular Function GO:0004029 (aldehyde dehydrogenase (NAD) activity)
GO:0004030 (aldehyde dehydrogenase [NAD(P)+] activity)
GO:0008106 (alcohol dehydrogenase (NADP+) activity)
GO Biological Process GO:0006081 (cellular aldehyde metabolic process)
Wikipedia Aldehyde_dehydrogenase_3_family,_member_A1

Target Cross References - Protein

Human Protein Atlas ENSG00000108602
PharmGKB PA24697
UniProt P30838 Q9BT37

Target Cross References - Domain

InterPro IPR012394 (Aldehyde_DH_NAD(P).)
IPR015590 (Aldehyde_DH_dom.)
IPR016160 (Ald_DH_CS.)
IPR016161 (Ald_DH/histidinol_DH.)
IPR016162 (Ald_DH_N.)
IPR016163 (Ald_DH_C.)
Pfam PF00171 (Aldedh)
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