ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3510
Target Type SINGLE PROTEIN
Preferred Name Carbonic anhydrase XIV
Synonyms CA-XIV | CA14 | Carbonate dehydratase XIV | Carbonic anhydrase 14 | Carbonic anhydrase XIV
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > lyase

Target Components

Component Description Relationship Accession
Carbonic anhydrase 14 SINGLE PROTEIN Q9ULX7

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095180 Carbonic anhydrase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000118298
Ensembl ENSG00000118298
GO Cellular Component GO:0005886 (plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0004089 (carbonate dehydratase activity)
GO:0016829 (lyase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0015701 (bicarbonate transport)
Wikipedia CA14

Target Cross References - Protein

canSAR Q9ULX7
Human Protein Atlas ENSG00000118298
IntAct Q9ULX7
Guide to Pharmacology 2598
Open Targets ENSG00000118298
PharmGKB PA25988
Reactome R-HSA-1475029 (Reversible hydration of carbon dioxide.)
UniProt Q5TB24 Q8NCF4 Q9ULX7

Target Cross References - Domain

InterPro IPR001148 (Carbonic_anhydrase_a.)
IPR018431 (Carbonic_anhydrase_CA14.)
IPR023561 (Carbonic_anhydrase_a-class.)
Pfam PF00194 (Carb_anhydrase)

Target Cross References - Structure

PDBe 4LU3 5CJF
CREDO 4LU3 5CJF
spacer
spacer