ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3381
Target Type SINGLE PROTEIN
Preferred Name Small conductance calcium-activated potassium channel protein 3
Synonyms K3 | KCNN3 | KCa2.3 | SK3 | SKCa 3 | SKCa3 | Small conductance calcium-activated potassium channel protein 3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • ion channel > voltage-gated ion channel > potassium channels > calcium-activated potassium channel

Target Components

Component Description Relationship Accession
Small conductance calcium-activated potassium channel protein 3 SINGLE PROTEIN Q9UGI6

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000143603
Ensembl ENSG00000143603
GO Cellular Component GO:0043025 (neuronal cell body)
GO:0016021 (integral component of membrane)
GO:0005886 (plasma membrane)
GO Molecular Function GO:0016286 (small conductance calcium-activated potassium channel activity)
GO:0005516 (calmodulin binding)
GO Biological Process GO:0007268 (synaptic transmission)
GO:0071805 (potassium ion transmembrane transport)
GO:1903955 (positive regulation of protein targeting to mitochondrion)
Wikipedia SK3

Target Cross References - Protein

canSAR Q9UGI6
Human Protein Atlas ENSG00000143603
Guide to Pharmacology 383 (KCa2.3)
PharmGKB PA30072
UniProt B1ANX0 O43517 Q9UGI6 Q8WXG7

Target Cross References - Domain

InterPro IPR015449 (K_chnl_Ca-activ_SK.)
IPR004178 (CaM-bd_dom.)
IPR013099 (K_chnl_dom.)
Pfam PF07885 (Ion_trans_2)
PF02888 (CaMBD)
PF03530 (SK_channel)
spacer
spacer