ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL3291
Target Type SINGLE PROTEIN
Preferred Name Phosphofructokinase muscle type
Synonyms 6-phosphofructokinase type A | ATP-PFK | ATP-dependent 6-phosphofructokinase, muscle type | PFK-A | PFK-M | PFKM | PFKX | Phosphofructo-1-kinase isozyme A | Phosphohexokinase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
ATP-dependent 6-phosphofructokinase, muscle type SINGLE PROTEIN P08237

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000152556
Ensembl ENSG00000152556
GO Cellular Component GO:0005945 (6-phosphofructokinase complex)
GO:0016324 (apical plasma membrane)
GO Molecular Function GO:0003872 (6-phosphofructokinase activity)
GO:0005524 (ATP binding)
GO:0008022 (protein C-terminus binding)
GO:0019900 (kinase binding)
GO:0042802 (identical protein binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006002 (fructose 6-phosphate metabolic process)
GO:0006096 (glycolysis)
GO:0046716 (muscle cell homeostasis)
Wikipedia PFKM

Target Cross References - Protein

canSAR P08237
CGD Glycogen storage disease VII
Human Protein Atlas ENSG00000152556
IntAct P08237
PharmGKB PA33216
Reactome REACT_474 (Metabolism of carbohydrates.)
UniProt P08237 Q16814 Q16815

Target Cross References - Domain

InterPro IPR000023 (Phosphofructokinase_dom.)
IPR009161 (6-phosphofructokinase_euk.)
IPR015912 (Phosphofructokinase_CS.)
IPR022953 (Phosphofructokinase.)
Pfam PF00365 (PFK)
spacer
spacer