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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3284
Target Type SINGLE PROTEIN
Preferred Name Alcohol dehydrogenase beta chain
Synonyms ADH1B | ADH2 | Alcohol dehydrogenase 1B | Alcohol dehydrogenase subunit beta
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > oxidoreductase

Target Components

Component Description Relationship Accession
Alcohol dehydrogenase 1B SINGLE PROTEIN P00325

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2363044 Alcohol dehydrogenase class I PROTEIN COMPLEX GROUP
CHEMBL2096668 Alcohol dehydrogenase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000196616
Ensembl ENSG00000196616
GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0004024 (alcohol dehydrogenase activity, zinc-dependent)
GO:0008270 (zinc ion binding)
GO Biological Process GO:0006069 (ethanol oxidation)
GO:0006805 (xenobiotic metabolic process)
Wikipedia ADH1B

Target Cross References - Protein

canSAR P00325
Human Protein Atlas ENSG00000196616
IntAct P00325
PharmGKB PA24571
Reactome REACT_13433 (Biological oxidations.)
UniProt P00325 Q13711 Q4ZGI9 Q96KI7

Target Cross References - Domain

InterPro IPR002085 (ADH_SF_Zn.)
IPR002328 (ADH_Zn_CS.)
IPR011032 (GroES-like.)
IPR013149 (ADH_C.)
IPR013154 (ADH_GroES-like.)
IPR016040 (NAD(P)-bd_dom.)
Pfam PF00107 (ADH_zinc_N)
PF08240 (ADH_N)

Target Cross References - Structure

PDBe 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD
CREDO 1DEH 1HDX 1HDY 1HDZ 1HSZ 1HTB 1U3U 1U3V 3HUD
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