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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3255
Target Type SINGLE PROTEIN
Preferred Name Activating transcription factor 1
Synonyms ATF1 | Activating transcription factor 1 | Cyclic AMP-dependent transcription factor ATF-1 | Protein TREB36 | cAMP-dependent transcription factor ATF-1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transcription factor

Target Components

Component Description Relationship Accession
Cyclic AMP-dependent transcription factor ATF-1 SINGLE PROTEIN P18846

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Expression Atlas ENSG00000123268
Ensembl ENSG00000123268
GO Biological Process GO:0002755 (MyD88-dependent toll-like receptor signaling pathway)
GO:0002756 (MyD88-independent toll-like receptor signaling pathway)
GO:0008063 (Toll signaling pathway)
GO:0034130 (toll-like receptor 1 signaling pathway)
GO:0034134 (toll-like receptor 2 signaling pathway)
GO:0034138 (toll-like receptor 3 signaling pathway)
GO:0034142 (toll-like receptor 4 signaling pathway)
GO:0045087 (innate immune response)
GO:0048011 (nerve growth factor receptor signaling pathway)
GO:0051403 (stress-activated MAPK cascade)
Wikipedia ATF1

Target Cross References - Protein

canSAR P18846
Human Protein Atlas ENSG00000123268
IntAct P18846
PharmGKB PA25083
Reactome REACT_11061 (Signalling by NGF.)
REACT_6900 (Signaling in Immune system.)
UniProt P18846 P25168 Q9H4A8

Target Cross References - Domain

InterPro IPR001630 (Leuzip_CREB.)
IPR003102 (Coactivator_CBP_pKID.)
IPR004827 (TF_bZIP.)
IPR011616 (bZIP_1.)
Pfam PF00170 (bZIP_1)
PF02173 (pKID)
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