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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3238
Target Type SINGLE PROTEIN
Preferred Name Carnitine palmitoyltransferase 2
Synonyms CPT II | CPT1 | CPT2 | Carnitine O-palmitoyltransferase 2, mitochondrial | Carnitine palmitoyltransferase II
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Carnitine O-palmitoyltransferase 2, mitochondrial SINGLE PROTEIN P23786

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000157184
Ensembl ENSG00000157184
GO Cellular Component GO:0005654 (nucleoplasm)
GO:0005730 (nucleolus)
GO:0005739 (mitochondrion)
GO:0005743 (mitochondrial inner membrane)
GO:0016020 (membrane)
GO Molecular Function GO:0004095 (carnitine O-palmitoyltransferase activity)
GO:0016740 (transferase activity)
GO:0016746 (transferase activity, transferring acyl groups)
GO Biological Process GO:0006629 (lipid metabolic process)
GO:0006631 (fatty acid metabolic process)
GO:0006635 (fatty acid beta-oxidation)
GO:0006810 (transport)
GO:0006853 (carnitine shuttle)
Wikipedia Carnitine_palmitoyltransferase_II

Target Cross References - Protein

canSAR P23786
CGD Carnitine palmitoyltransferase II deficiency
Human Protein Atlas ENSG00000157184
IntAct P23786
Open Targets ENSG00000157184
PharmGKB PA26849
Reactome R-HSA-1989781 (PPARA activates gene expression.)
R-HSA-200425 (Import of palmitoyl-CoA into the mitochondrial matrix.)
UniProt B2R6S0 P23786 Q5SW68 Q9BQ26

Target Cross References - Domain

InterPro IPR000542 (Carn_acyl_trans.)
Pfam PF00755 (Carn_acyltransf)
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