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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3202
Target Type SINGLE PROTEIN
Preferred Name Prolyl endopeptidase
Synonyms PE | PEP | PREP | Post-proline cleaving enzyme | Prolyl endopeptidase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease > serine protease sc clan > serine protease s9a subfamily

Target Components

Component Description Relationship Accession
Prolyl endopeptidase SINGLE PROTEIN P48147

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000085377
Ensembl ENSG00000085377
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
Wikipedia Prolyl_endopeptidase

Target Cross References - Protein

canSAR P48147
Human Protein Atlas ENSG00000085377
IntAct P48147
Guide to Pharmacology 2395 (prolyl endopeptidase)
PharmGKB PA33730
UniProt P48147 Q8N6D4

Target Cross References - Domain

InterPro IPR001375 (Peptidase_S9.)
IPR002470 (Peptidase_S9A.)
IPR002471 (Pept_S9_AS.)
IPR004106 (Peptidase_S9A_B_C_N.)
IPR023302 (Pept_S9A_oligopept_N.)
Pfam PF00326 (Peptidase_S9)
PF02897 (Peptidase_S9_N)

Target Cross References - Structure

PDBe 3DDU
CREDO 3DDU
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