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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3194
Target Type SINGLE PROTEIN
Preferred Name Transthyretin
Synonyms ATTR | PALB | Prealbumin | TBPA | TTR | Transthyretin
Organism Homo sapiens
Species Group No
Protein Target Classification
  • unclassified protein

Target Components

Component Description Relationship Accession
Transthyretin SINGLE PROTEIN P02766

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000118271
Ensembl ENSG00000118271
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0005179 (hormone activity)
GO Biological Process GO:0006810 (transport)
Wikipedia Transthyretin

Target Cross References - Protein

canSAR P02766
CGD Amyloidosis, hereditary, transthyretin-related; Dystransthyretinemic hyperthyroxinemia
Human Protein Atlas ENSG00000118271
IntAct P02766
PharmGKB PA37069
TIMBAL Transthyretin
UniProt P02766 Q549C7 Q6IB96 Q9UBZ6 Q9UCM9

Target Cross References - Domain

InterPro IPR000895 (Transthyretin/HIU_hydrolase.)
IPR023416 (Transthyretin/HIU_hydrolase_SF.)
IPR023418 (Thyroxine_BS.)
IPR023419 (Transthyretin_CS.)
Pfam PF00576 (Transthyretin)

Target Cross References - Structure

PDBe 1BM7 1BMZ 1BZ8 1BZD 1BZE 1DVQ 1DVS 1DVT 1DVU 1DVX 1DVY 1DVZ 1E3F 1E4H 1E5A 1ETA 1ETB 1F41 1F86 1FH2 1FHN 1G1O 1GKO 1ICT More...
CREDO 1BM7 1BMZ 1BZ8 1BZD 1BZE 1DVQ 1DVS 1DVT 1DVU 1DVX 1DVY 1DVZ 1E3F 1E4H 1E5A 1ETA 1ETB 1F41 1F86 1FH2 1FHN 1G1O 1GKO 1ICT More...
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