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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3163
Target Type SINGLE PROTEIN
Preferred Name NF-kappa-B-repressing factor
Synonyms ITBA4 | NF-kappa-B-repressing factor | NFkB-repressing factor | NKRF | NRF | Protein ITBA4 | Transcription factor NRF
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transcription factor

Target Components

Component Description Relationship Accession
NF-kappa-B-repressing factor SINGLE PROTEIN O15226

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000186416
Ensembl ENSG00000186416
GO Cellular Component GO:0005634 (nucleus)
GO:0005730 (nucleolus)
GO:0005783 (endoplasmic reticulum)
GO Molecular Function GO:0003676 (nucleic acid binding)
GO:0003677 (DNA binding)
GO:0005515 (protein binding)
GO:0044822 (poly(A) RNA binding)
GO Biological Process GO:0006351 (transcription, DNA-templated)
GO:0006355 (regulation of transcription, DNA-templated)
GO:0045892 (negative regulation of transcription, DNA-templated)
Wikipedia NKRF_(gene)

Target Cross References - Protein

canSAR O15226
Human Protein Atlas ENSG00000186416
IntAct O15226
Open Targets ENSG00000186416
PharmGKB PA134990602
UniProt G3V1N1 O15226 Q4VC41 Q9UJ91

Target Cross References - Domain

InterPro IPR000467 (G_patch_dom.)
IPR001374 (R3H_dom.)
IPR014720 (dsRBD_dom.)
IPR034071 (R3H_NRF.)
Pfam PF01424 (R3H)
PF01585 (G-patch)
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