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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3117
Target Type SINGLE PROTEIN
Preferred Name Choline kinase alpha
Synonyms CHETK-alpha | CHK | CHKA | CK | CKI | Choline kinase alpha | EK | Ethanolamine kinase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Choline kinase alpha SINGLE PROTEIN P35790

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Expression Atlas ENSG00000110721
Ensembl ENSG00000110721
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004103 (choline kinase activity)
GO:0004305 (ethanolamine kinase activity)
GO:0004871 (signal transducer activity)
GO:0005524 (ATP binding)
GO:0008144 (drug binding)
GO Biological Process GO:0006646 (phosphatidylethanolamine biosynthetic process)
GO:0006869 (lipid transport)
Wikipedia CHKA

Target Cross References - Protein

canSAR P35790
Human Protein Atlas ENSG00000110721
IntAct P35790
MICAD NBK23549 (Choline kinase)
PharmGKB PA26468
UniProt P35790 Q8NE29

Target Cross References - Domain

InterPro IPR002573 (Choline/ethanolamine_kinase.)
IPR011009 (Kinase-like_dom.)
Pfam PF01633 (Choline_kinase)

Target Cross References - Structure

PDBe 2CKO 2CKP 2CKQ 2I7Q 3F2R 3G15
CREDO 2CKO 2CKP 2CKQ 2I7Q 3F2R 3G15
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