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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3060
Target Type SINGLE PROTEIN
Preferred Name Glycine transporter 2
Synonyms GLYT2 | GlyT-2 | GlyT2 | NET1 | SLC6A5 | Sodium- and chloride-dependent glycine transporter 2 | Solute carrier family 6 member 5
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc06 neurotransmitter transporter family

Target Components

Component Description Relationship Accession
Sodium- and chloride-dependent glycine transporter 2 SINGLE PROTEIN Q9Y345

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000165970
Ensembl ENSG00000165970
GO Cellular Component GO:0005886 (plasma membrane)
GO:0016021 (integral to membrane)
GO Molecular Function GO:0005328 (neurotransmitter:sodium symporter activity)
GO:0015375 (glycine:sodium symporter activity)
GO Biological Process GO:0007268 (synaptic transmission)
Wikipedia Glycine_transporter_2

Target Cross References - Protein

CGD Hyperekplexia 3
Human Protein Atlas ENSG00000165970
Guide to Pharmacology 936 (GlyT2)
PharmGKB PA35911
Reactome REACT_15518 (Transmembrane transport of small molecules.)
REACT_20679 (Amine compound SLC transporters.)
UniProt O95288 Q4VAM7 Q9BX77 Q9Y345

Target Cross References - Domain

InterPro IPR000175 (Na/ntran_symport.)
Pfam PF00209 (SNF)
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