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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3040
Preferred Name CDC45-related protein
Synonyms CDC45 | CDC45L | CDC45L2 | Cell division control protein 45 homolog | PORC-PI-1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • other cytosolic protein
  • other nuclear protein

Target Components

Component Description Relationship Accession
Cell division control protein 45 homolog SINGLE PROTEIN O75419

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000093009
Ensembl ENSG00000093009
GO Cellular Component GO:0005654 (nucleoplasm)
GO:0005813 (centrosome)
GO Molecular Function GO:0005515 (protein binding)
GO Biological Process GO:0000076 (DNA replication checkpoint)
GO:0000083 (regulation of transcription involved in G1/S phase of mitotic cell cycle)
GO:0000084 (S phase of mitotic cell cycle)
GO:0000216 (M/G1 transition of mitotic cell cycle)
GO:0006270 (DNA-dependent DNA replication initiation)
GO:0006271 (DNA strand elongation involved in DNA replication)
Wikipedia CDC45-related_protein

Target Cross References - Protein

canSAR O75419
Human Protein Atlas ENSG00000093009
IntAct O75419
PharmGKB PA371
Reactome REACT_152 (Cell Cycle, Mitotic.)
REACT_1538 (Cell Cycle Checkpoints.)
REACT_383 (DNA Replication.)
UniProt O60856 O75419 Q20WK8 Q6UW54 Q9UP68

Target Cross References - Domain

InterPro IPR003874 (CDC45.)
Pfam PF02724 (CDC45)