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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL3019
Preferred Name Cytochrome P450 3A5
Synonyms Object
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > cytochrome p450 > cytochrome p450 family 3 > cytochrome p450 family 3a > cytochrome p450 3a5

Target Components

Component Description Relationship Accession
Cytochrome P450 3A5 SINGLE PROTEIN P20815

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2364675 Cytochrome P450 3A PROTEIN FAMILY
CHEMBL2111472 Cytochrome P450 3A4/3A5 PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000106258
Ensembl ENSG00000106258
GO Cellular Component GO:0043231 (intracellular membrane-bounded organelle)
GO:0005789 (endoplasmic reticulum membrane)
GO Molecular Function GO:0004497 (monooxygenase activity)
GO:0005506 (iron ion binding)
GO:0016491 (oxidoreductase activity)
GO:0070330 (aromatase activity)
GO:0019825 (oxygen binding)
GO:0020037 (heme binding)
GO Biological Process GO:0009822 (alkaloid catabolic process)
GO:0008202 (steroid metabolic process)
GO:0044281 (small molecule metabolic process)
GO:0006805 (xenobiotic metabolic process)
GO:0042737 (drug catabolic process)
GO:0070989 (oxidative demethylation)
Wikipedia CYP3A5

Target Cross References - Protein

canSAR P20815
CGD Drug metabolism, CYP3A5-related
Human Protein Atlas ENSG00000106258
IntAct P20815
Guide to Pharmacology 1338 (CYP3A5)
PharmGKB PA131
UniProt P20815 A4D289 Q9HB56 Q53WY8 Q75MV0

Target Cross References - Domain

InterPro IPR008072 (Cyt_P450_E_CYP3A.)
IPR017972 (Cyt_P450_CS.)
IPR002402 (Cyt_P450_E_grp-II.)
IPR001128 (Cyt_P450.)
Pfam PF00067 (p450)