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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2940
Target Type SINGLE PROTEIN
Preferred Name Immunoglobulin epsilon Fc receptor
Synonyms BLAST-2 | C-type lectin domain family 4 member J | CD23A | CD_antigen=CD23 | CLEC4J | FCE2 | FCER2 | Fc-epsilon-RII | IGEBF | Immunoglobulin E-binding factor | Low affinity immunoglobulin epsilon Fc receptor | Low affinity immunoglobulin epsilon Fc receptor membrane-bound form | Low affinity immunoglobulin epsilon Fc receptor soluble form | Lymphocyte IgE receptor
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor

Target Components

Component Description Relationship Accession
Low affinity immunoglobulin epsilon Fc receptor SINGLE PROTEIN P06734

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000104921
Ensembl ENSG00000104921
GO Cellular Component GO:0005576 (extracellular region)
GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0004872 (receptor activity)
GO:0005178 (integrin binding)
GO:0005529 (sugar binding)
GO:0019863 (IgE binding)
GO Biological Process GO:0051000 (positive regulation of nitric-oxide synthase activity)
GO:0051712 (positive regulation of killing of cells of other organism)
GO:0051773 (positive regulation of nitric-oxide synthase 2 biosynthetic process)
Wikipedia CD23

Target Cross References - Protein

canSAR P06734
Human Protein Atlas ENSG00000104921
PharmGKB PA28058

Target Cross References - Domain

InterPro IPR001304 (C-type_lectin.)
IPR002353 (AntifreezeII.)
IPR016186 (C-type_lectin-like.)
IPR016187 (C-type_lectin_fold.)
IPR018378 (C-type_lectin_CS.)
Pfam PF00059 (Lectin_C)

Target Cross References - Structure

PDBe 2H2R 2H2T
CREDO 2H2R 2H2T
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