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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2912
Target Type SINGLE PROTEIN
Preferred Name AMP deaminase 3
Synonyms AMP deaminase 3 | AMP deaminase isoform E | AMPD3 | Erythrocyte AMP deaminase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
AMP deaminase 3 SINGLE PROTEIN Q01432

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000133805
Ensembl ENSG00000133805
GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0003876 (AMP deaminase activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006144 (purine base metabolic process)
GO:0006144 (purine nucleobase metabolic process)
GO:0006196 (AMP catabolic process)
GO:0009168 (purine ribonucleoside monophosphate biosynthetic process)
GO:0032264 (IMP salvage)
GO:0034101 (erythrocyte homeostasis)
GO:0043101 (purine-containing compound salvage)
GO:0044281 (small molecule metabolic process)
GO:0046031 (ADP metabolic process)
GO:0046034 (ATP metabolic process)
GO:0046039 (GTP metabolic process)
GO:0055086 (nucleobase-containing small molecule metabolic process)
GO:0097009 (energy homeostasis)
Wikipedia AMPD3

Target Cross References - Protein

canSAR Q01432
CGD Erythrocytic AMP deaminase deficiency
Human Protein Atlas ENSG00000133805
IntAct Q01432
PharmGKB PA24778
UniProt B7Z877 Q01432

Target Cross References - Domain

InterPro IPR001365 (A/AMP_deaminase.)
IPR001365 (A/AMP_deaminase_dom.)
IPR006329 (AMPD.)
IPR006329 (AMP_deaminase.)
IPR006650 (A/AMP_deam_AS.)
IPR016297 (AMP_deaminase_met.)
IPR029771 (AMPD3.)
IPR032466 (Metal_Hydrolase.)
Pfam PF00962 (A_deaminase)
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