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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2888
Target Type SINGLE PROTEIN
Preferred Name Metabotropic glutamate receptor 3
Synonyms GPRC1C | GRM3 | MGLUR3 | Metabotropic glutamate receptor 3 | mGluR3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family c g protein-coupled receptor > small molecule receptor (family c gpcr) > neurotransmitter receptor (family c gpcr) > metabotropic glutamate receptor

Target Components

Component Description Relationship Accession
Metabotropic glutamate receptor 3 SINGLE PROTEIN Q14832

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000198822
Ensembl ENSG00000198822
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Biological Process GO:0007268 (synaptic transmission)
Wikipedia Metabotropic_glutamate_receptor_3

Target Cross References - Protein

canSAR Q14832
Human Protein Atlas ENSG00000198822
Guide to Pharmacology 291 (mGlu3)
PharmGKB PA28992
Reactome REACT_14797 (Signaling by GPCR.)
UniProt Q14832 Q75MV4 Q75N17 Q86YG6 Q8TBH9

Target Cross References - Domain

InterPro IPR000162 (GPCR_3_mtglu_rcpt.)
IPR000337 (GPCR_3.)
IPR001234 (GPCR_3_mtglu_rcpt_3.)
IPR001828 (ANF_lig-bd_rcpt.)
IPR011500 (GPCR_3_9-Cys_dom.)
IPR017978 (GPCR_3_C.)
IPR017979 (GPCR_3_CS.)
Pfam PF00003 (7tm_3)
PF01094 (ANF_receptor)
PF07562 (NCD3G)
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