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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2885
Target Type SINGLE PROTEIN
Preferred Name Carbonic anhydrase III
Synonyms CA-III | CA3 | Carbonate dehydratase III | Carbonic anhydrase 3 | Carbonic anhydrase III
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > lyase

Target Components

Component Description Relationship Accession
Carbonic anhydrase 3 SINGLE PROTEIN P07451

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095180 Carbonic anhydrase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000164879
Ensembl ENSG00000164879
GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0004089 (carbonate dehydratase activity)
GO:0016151 (nickel cation binding)
GO:0008270 (zinc ion binding)
GO:0016791 (phosphatase activity)
GO Biological Process GO:0044281 (small molecule metabolic process)
GO:0045471 (response to ethanol)
GO:0006730 (one-carbon metabolic process)
GO:0015701 (bicarbonate transport)
GO:0006979 (response to oxidative stress)
Wikipedia Carbonic_anhydrase_III,_muscle_specific

Target Cross References - Protein

canSAR P07451
Human Protein Atlas ENSG00000164879
PharmGKB PA25990
UniProt O60842 B3KUC8 P07451 B2R867

Target Cross References - Domain

InterPro IPR018338 (Carbonic_anhydrase_a-class_CS.)
IPR001148 (Carbonic_anhydrase_a.)
IPR018441 (Carbonic_anhydrase_CA3.)
IPR023561 (Carbonic_anhydrase_a-class.)
Pfam PF00194 (Carb_anhydrase)

Target Cross References - Structure

PDBe 1Z93 3UYN 2HFW 3UYQ 1Z97
CREDO 1Z93 3UYN 2HFW 3UYQ 1Z97
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