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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2761
Target Type SINGLE PROTEIN
Preferred Name Aspartyl aminopeptidase
Synonyms ASPEP | Aspartyl aminopeptidase | DAP | DNPEP
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mh clan > metallo protease m18 family

Target Components

Component Description Relationship Accession
Aspartyl aminopeptidase SINGLE PROTEIN Q9ULA0

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000123992
Ensembl ENSG00000123992
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0004177 (aminopeptidase activity)
GO:0005515 (protein binding)
GO:0008237 (metallopeptidase activity)
GO:0008270 (zinc ion binding)
GO Biological Process GO:0006508 (proteolysis)
GO:0006518 (peptide metabolic process)
Wikipedia DNPEP

Target Cross References - Protein

canSAR Q9ULA0
Human Protein Atlas ENSG00000123992
IntAct Q9ULA0
Guide to Pharmacology 1559 (Aminopeptidase A)
PharmGKB PA27448
UniProt Q9BW44 Q9NUV5 Q9ULA0

Target Cross References - Domain

InterPro IPR001948 (Peptidase_M18.)
IPR023358 (Peptidase_M18_dom2.)
Pfam PF02127 (Peptidase_M18)

Target Cross References - Structure

PDBe 3L6S
CREDO 3L6S
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