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Target Report Card

Target Name and Classification

Target ID CHEMBL2731
Preferred Name Galanin receptor 3
Synonyms GAL3-R | GALNR3 | GALR-3 | GALR3 | Galanin receptor type 3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > galanin receptor

Target Components

Component Description Relationship Accession
Galanin receptor type 3 SINGLE PROTEIN O60755

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000128310
Ensembl ENSG00000128310
GO Cellular Component GO:0005886 (plasma membrane)
GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0097730 (non-motile cilium)
GO Molecular Function GO:0004871 (signal transducer activity)
GO:0004930 (G-protein coupled receptor activity)
GO:0004966 (galanin receptor activity)
GO:0017046 (peptide hormone binding)
GO Biological Process GO:0007165 (signal transduction)
GO:0007186 (G-protein coupled receptor signaling pathway)
GO:0007187 (G-protein coupled receptor signaling pathway, coupled to cyclic nucleotide second messenger)
GO:0007188 (adenylate cyclase-modulating G-protein coupled receptor signaling pathway)
GO:0007194 (negative regulation of adenylate cyclase activity)
GO:0007200 (phospholipase C-activating G-protein coupled receptor signaling pathway)
GO:0007218 (neuropeptide signaling pathway)
GO:0007268 (chemical synaptic transmission)
GO:0007611 (learning or memory)
GO:0007631 (feeding behavior)
GO:0045944 (positive regulation of transcription from RNA polymerase II promoter)
GO:0090663 (galanin-activated signaling pathway)
Wikipedia Galanin_receptor_3

Target Cross References - Protein

canSAR O60755
Human Protein Atlas ENSG00000128310
Guide to Pharmacology 245
Open Targets ENSG00000128310
PharmGKB PA28547
Pharos O60755 (Tchem)
Reactome R-HSA-375276 (Peptide ligand-binding receptors.)
R-HSA-418594 (G alpha (i) signalling events.)
UniProt O60755 Q53YJ4

Target Cross References - Domain

InterPro IPR000276 (GPCR_Rhodpsn.)
IPR000405 (Galanin_rcpt.)
IPR003908 (Galnin_3_rcpt.)
IPR017452 (GPCR_Rhodpsn_7TM.)
Pfam PF00001 (7tm_1)