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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2655
Target Type SINGLE PROTEIN
Preferred Name Adenylate cyclase type IX
Synonyms ADCY9 | ATP pyrophosphate-lyase 9 | Adenylate cyclase type 9 | Adenylate cyclase type IX | Adenylyl cyclase 9 | KIAA0520
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Adenylate cyclase type 9 SINGLE PROTEIN O60503

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2097167 Adenylate cyclase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000162104
Ensembl ENSG00000162104
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0004016 (adenylate cyclase activity)
GO:0005524 (ATP binding)
GO:0046872 (metal ion binding)
GO Biological Process GO:0006112 (energy reserve metabolic process)
GO:0006833 (water transport)
GO:0007189 (activation of adenylate cyclase activity by G-protein signaling pathway)
GO:0007193 (inhibition of adenylate cyclase activity by G-protein signaling pathway)
GO:0007202 (activation of phospholipase C activity)
GO:0007268 (synaptic transmission)
GO:0034199 (activation of protein kinase A activity)
GO:0048011 (nerve growth factor receptor signaling pathway)
GO:0055085 (transmembrane transport)
GO:0071377 (cellular response to glucagon stimulus)
Wikipedia ADCY9

Target Cross References - Protein

canSAR O60503
Human Protein Atlas ENSG00000162104
Guide to Pharmacology 1286 (AC9)
PharmGKB PA30
Reactome REACT_11061 (Signalling by NGF.)
REACT_13685 (Synaptic Transmission.)
REACT_14797 (Signaling by GPCR.)
REACT_1505 (Integration of energy metabolism.)
REACT_15295 (Opioid Signalling.)
REACT_15518 (Transmembrane transport of small molecules.)
UniProt A7E2V5 D3DUD1 O60273 O60503 Q4ZHT9 Q4ZIR5 Q9BWT4 Q9UGP2

Target Cross References - Domain

InterPro IPR001054 (A/G_cyclase.)
IPR018297 (A/G_cyclase_CS.)
Pfam PF00211 (Guanylate_cyc)
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