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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2517
Target Type SINGLE PROTEIN
Preferred Name Cathepsin F
Synonyms CATSF | CTSF | Cathepsin F
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > cysteine protease > cysteine protease ca clan > cysteine protease c1a family

Target Components

Component Description Relationship Accession
Cathepsin F SINGLE PROTEIN Q9UBX1

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000174080
Ensembl ENSG00000174080
GO Cellular Component GO:0005615 (extracellular space)
GO:0005764 (lysosome)
GO:0043202 (lysosomal lumen)
GO:0070062 (extracellular exosome)
GO:1903561 (extracellular vesicle)
GO Molecular Function GO:0004197 (cysteine-type endopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0019886 (antigen processing and presentation of exogenous peptide antigen via MHC class II)
GO:0051603 (proteolysis involved in cellular protein catabolic process)
Wikipedia Cathepsin_F

Target Cross References - Protein

canSAR Q9UBX1
CGD Kufs disease, type B, autosomal recessive
Human Protein Atlas ENSG00000174080
PharmGKB PA27031
UniProt B2R964 O95240 Q9NSU4 Q9UBX1 Q9UKQ5

Target Cross References - Domain

InterPro IPR000169 (Pept_cys_AS.)
IPR000668 (Peptidase_C1A_C.)
IPR013128 (Peptidase_C1A.)
IPR013201 (Prot_inhib_I29.)
IPR025660 (Pept_his_AS.)
Pfam PF00112 (Peptidase_C1)
PF08246 (Inhibitor_I29)

Target Cross References - Structure

PDBe 1M6D
CREDO 1M6D
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