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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2432
Target Type SINGLE PROTEIN
Preferred Name Aminopeptidase B
Synonyms AP-B | APB | Aminopeptidase B | Arginine aminopeptidase | Arginyl aminopeptidase | RNPEP
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > metallo protease > metallo protease mae clan > metallo protease m1 family

Target Components

Component Description Relationship Accession
Aminopeptidase B SINGLE PROTEIN Q9H4A4

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000176393
Ensembl ENSG00000176393
GO Molecular Function GO:0004301 (epoxide hydrolase activity)
GO:0008270 (zinc ion binding)
GO Biological Process GO:0019370 (leukotriene biosynthetic process)
Wikipedia RNPEP

Target Cross References - Protein

canSAR Q9H4A4
Human Protein Atlas ENSG00000176393
Guide to Pharmacology 1564 (Arginyl aminopeptidase)
PharmGKB PA34451
UniProt Q9BVM9 Q9H1D4 Q9H4A4 Q9NPT7

Target Cross References - Domain

InterPro IPR001930 (Peptidase_M1.)
IPR014782 (Peptidase_M1_N.)
IPR015211 (Peptidase_M1_C.)
IPR015571 (Pept_M1_aminopeptidase-B.)
IPR016024 (ARM-type_fold.)
Pfam PF01433 (Peptidase_M1)
PF09127 (Leuk-A4-hydro_C)
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