ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL2422
Target Type SINGLE PROTEIN
Preferred Name G1/S-specific cyclin D3
Synonyms CCND3 | G1/S-specific cyclin-D3
Organism Homo sapiens
Species Group No
Protein Target Classification
  • other cytosolic protein

Target Components

Component Description Relationship Accession
G1/S-specific cyclin-D3 SINGLE PROTEIN P30281

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2095942 Cyclin-dependent kinase 4/cyclin D PROTEIN COMPLEX
CHEMBL2111448 CDK6/cyclin D3 PROTEIN COMPLEX
CHEMBL3038472 CDK4/Cyclin D3 PROTEIN COMPLEX

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000112576
Ensembl ENSG00000112576
GO Cellular Component GO:0000307 (cyclin-dependent protein kinase holoenzyme complex)
GO:0005634 (nucleus)
GO:0005737 (cytoplasm)
GO:0016020 (membrane)
GO Molecular Function GO:0019901 (protein kinase binding)
GO Biological Process GO:0001934 (positive regulation of protein phosphorylation)
GO:0045737 (positive regulation of cyclin-dependent protein kinase activity)
GO:0051301 (cell division)
Wikipedia Cyclin_D3

Target Cross References - Protein

canSAR P30281
Human Protein Atlas ENSG00000112576
IntAct P30281
PharmGKB PA26152
Reactome REACT_152 (Cell Cycle, Mitotic.)
UniProt B2RD63 P30281 Q5T8J0 Q6FG62 Q96F49

Target Cross References - Domain

InterPro IPR004367 (Cyclin_C.)
IPR006671 (Cyclin_N.)
IPR013763 (Cyclin-like.)
IPR014400 (Cyclin_A/B/D/E.)
Pfam PF00134 (Cyclin_N)
PF02984 (Cyclin_C)

Target Cross References - Structure

PDBe 3G33
CREDO 3G33
spacer
spacer