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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2421
Target Type SINGLE PROTEIN
Preferred Name Corticosteroid binding globulin
Synonyms CBG | CBG | Corticosteroid-binding globulin | SERPINA6 | Serpin A6 | Transcortin
Organism Homo sapiens
Species Group No
Protein Target Classification
  • secreted protein

Target Components

Component Description Relationship Accession
Corticosteroid-binding globulin SINGLE PROTEIN P08185

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000170099 ENSG00000277405
Ensembl ENSG00000170099 ENSG00000277405
GO Cellular Component GO:0005576 (extracellular region)
GO:0005615 (extracellular space)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0004867 (serine-type endopeptidase inhibitor activity)
GO:0005496 (steroid binding)
GO:0008289 (lipid binding)
GO Biological Process GO:0006810 (transport)
GO:0008211 (glucocorticoid metabolic process)
GO:0010951 (negative regulation of endopeptidase activity)
Wikipedia Transcortin

Target Cross References - Protein

canSAR P08185
CGD Corticosteroid-binding globulin deficiency
Human Protein Atlas ENSG00000170099 ENSG00000277405
Open Targets ENSG00000170099 ENSG00000277405
PharmGKB PA35033
UniProt A8K456 P08185 Q7Z2Q9

Target Cross References - Domain

InterPro IPR000215 (Serpin_fam.)
IPR023795 (Serpin_CS.)
IPR023796 (Serpin_dom.)
Pfam PF00079 (Serpin)

Target Cross References - Structure

PDBe 2VDX 2VDY 4BB2 4C41 4C49
CREDO 2VDX 2VDY 4BB2 4C41 4C49
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