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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2349
Target Type SINGLE PROTEIN
Preferred Name Phosphorylase kinase gamma subunit 2
Synonyms PHK-gamma-LT | PHK-gamma-T | PHKG2 | PSK-C3 | Phosphorylase b kinase gamma catalytic chain, liver/testis isoform | Phosphorylase kinase subunit gamma-2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > kinase > protein kinase > camk protein kinase group > camk protein kinase phk family

Target Components

Component Description Relationship Accession
Phosphorylase b kinase gamma catalytic chain, liver/testis isoform SINGLE PROTEIN P15735

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2111324 Phosphorylase kinase PROTEIN COMPLEX GROUP

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000156873
Ensembl ENSG00000156873
GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0004689 (phosphorylase kinase activity)
GO:0005516 (calmodulin binding)
GO:0005524 (ATP binding)
GO Biological Process GO:0005978 (glycogen biosynthetic process)
GO:0005980 (glycogen catabolic process)
GO:0006006 (glucose metabolic process)
GO:0006468 (protein phosphorylation)
Wikipedia PHKG2

Target Cross References - Protein

canSAR P15735
CGD Glycogen storage disease IXc
Human Protein Atlas ENSG00000156873
IntAct P15735
Guide to Pharmacology 2147 (phosphorylase kinase, gamma 2 (testis))
PharmGKB PA33272
Reactome REACT_474 (Metabolism of carbohydrates.)
UniProt A8K0C7 B4DEB7 E9PEU3 P11800 P15735

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_cat_dom.)
IPR002290 (Ser/Thr_prot_kinase_dom.)
IPR002291 (Phosph_kin_gamma.)
IPR008271 (Ser/Thr_prot_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
IPR017442 (Se/Thr_prot_kinase-like_dom.)
IPR020636 (Ca/CaM-dep_prot_kinase-like.)
Pfam PF00069 (Pkinase)

Target Cross References - Structure

PDBe 2Y7J
CREDO 2Y7J
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