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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2241
Target Type SINGLE PROTEIN
Preferred Name Glutathione S-transferase A2
Synonyms GST HA subunit 2 | GST class-alpha member 2 | GST-gamma | GST2 | GSTA2 | GSTA2-2 | GTH2 | Glutathione S-transferase A2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Glutathione S-transferase A2 SINGLE PROTEIN P09210

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000244067
Ensembl ENSG00000244067
GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0004364 (glutathione transferase activity)
GO Biological Process GO:0006749 (glutathione metabolic process)
GO:0006805 (xenobiotic metabolic process)
Wikipedia GSTA2

Target Cross References - Protein

canSAR P09210
Human Protein Atlas ENSG00000244067
PharmGKB PA29017
Reactome REACT_13433 (Biological oxidations.)
UniProt P09210 Q12759 Q16491 Q9NTY6

Target Cross References - Domain

InterPro IPR003080 (GST_alpha.)
IPR004045 (Glutathione_S-Trfase_N.)
IPR004046 (GST_C.)
IPR010987 (Glutathione-S-Trfase_C-like.)
IPR012335 (Thioredoxin_fold.)
IPR012336 (Thioredoxin-like_fold.)
IPR017933 (Glutathione_S_Trfase/Cl_chnl_C.)
Pfam PF00043 (GST_C)
PF02798 (GST_N)

Target Cross References - Structure

PDBe 1AGS 2VCT 2WJU
CREDO 1AGS 2VCT 2WJU
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