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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2194
Target Type SINGLE PROTEIN
Preferred Name Arylamine N-acetyltransferase 2
Synonyms AAC2 | Arylamide acetylase 2 | Arylamine N-acetyltransferase 2 | N-acetyltransferase type 2 | NAT-2 | NAT2 | PNAT | Polymorphic arylamine N-acetyltransferase
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Arylamine N-acetyltransferase 2 SINGLE PROTEIN P11245

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000156006
Ensembl ENSG00000156006
GO Cellular Component GO:0005829 (cytosol)
GO Molecular Function GO:0004060 (arylamine N-acetyltransferase activity)
GO Biological Process GO:0006805 (xenobiotic metabolic process)
Wikipedia N-acetyltransferase_2

Target Cross References - Protein

canSAR P11245
CGD Acetylation, NAT2-related
Human Protein Atlas ENSG00000156006
PharmGKB PA18
Reactome REACT_13433 (Biological oxidations.)
UniProt O43637 O60654 O60655 P11245 Q13146 Q16697 Q2MLE4 Q2MLF5 Q2MLG8 Q2MLJ6 Q2MLK4 Q2MLK6 Q2MLN7 Q6LET4 Q86XS0 Q86XS1 Q96KY8 Q96T64 Q96T65 Q9H220

Target Cross References - Domain

InterPro IPR001447 (N-AcTrfase.)
Pfam PF00797 (Acetyltransf_2)

Target Cross References - Structure

PDBe 2PFR
CREDO 2PFR
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