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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2141
Target Type SINGLE PROTEIN
Preferred Name Glutathione S-transferase theta 1
Synonyms GST class-theta-1 | GSTT1 | Glutathione S-transferase theta-1 | Glutathione transferase T1-1
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Glutathione S-transferase theta-1 SINGLE PROTEIN P30711

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000277656
Ensembl ENSG00000277656
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO:0070062 (extracellular exosome)
GO Molecular Function GO:0004364 (glutathione transferase activity)
GO:0004602 (glutathione peroxidase activity)
GO:0016740 (transferase activity)
GO Biological Process GO:0006749 (glutathione metabolic process)
GO:0098869 (cellular oxidant detoxification)
GO:1901687 (glutathione derivative biosynthetic process)
Wikipedia GSTT1

Target Cross References - Protein

canSAR P30711
Human Protein Atlas ENSG00000277656
IntAct P30711
Open Targets ENSG00000277656
PharmGKB PA183
Reactome R-HSA-156590 (Glutathione conjugation.)
UniProt O00226 P30711 Q5TZY2 Q6IC69 Q969K8 Q96IY3

Target Cross References - Domain

InterPro IPR004045 (Glutathione_S-Trfase_N.)
IPR004046 (GST_C.)
IPR010987 (Glutathione-S-Trfase_C-like.)
IPR012336 (Thioredoxin-like_fold.)
Pfam PF00043 (GST_C)
PF13417 (GST_N_3)

Target Cross References - Structure

PDBe 2C3N 2C3Q 2C3T
CREDO 2C3N 2C3Q 2C3T
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