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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2121
Target Type SINGLE PROTEIN
Preferred Name Folate receptor alpha
Synonyms Adult folate-binding protein | FBP | FOLR | FOLR1 | FR-alpha | Folate receptor 1 | Folate receptor alpha | Folate receptor, adult | KB cells FBP | Ovarian tumor-associated antigen MOv18
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor

Target Components

Component Description Relationship Accession
Folate receptor alpha SINGLE PROTEIN P15328

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Expression Atlas ENSG00000110195
Ensembl ENSG00000110195
GO Cellular Component GO:0005576 (extracellular region)
GO:0005624 (membrane fraction)
GO:0005887 (integral to plasma membrane)
GO:0031225 (anchored to membrane)
GO Molecular Function GO:0004872 (receptor activity)
GO:0005542 (folic acid binding)
GO Biological Process GO:0006898 (receptor-mediated endocytosis)
GO:0008219 (cell death)
GO:0015884 (folic acid transport)
Wikipedia Folate_receptor_1

Target Cross References - Protein

canSAR P15328
CGD Cerebral folate deficiency
Human Protein Atlas ENSG00000110195
PharmGKB PA28207
UniProt P15328 Q53EW2 Q6FGT8 Q6LC90 Q9UCT2

Target Cross References - Domain

InterPro IPR004269 (Folate_rcpt.)
IPR018143 (Folate_rcpt-like.)
Pfam PF03024 (Folate_rec)
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