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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2100
Target Type SINGLE PROTEIN
Preferred Name Glutathione S-transferase Mu 4
Synonyms GST class-mu 4 | GST-Mu2 | GSTM4 | GSTM4-4 | Glutathione S-transferase Mu 4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Glutathione S-transferase Mu 4 SINGLE PROTEIN Q03013

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000168765
Ensembl ENSG00000168765
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005829 (cytosol)
GO Molecular Function GO:0004364 (glutathione transferase activity)
GO:0005515 (protein binding)
GO:0016740 (transferase activity)
GO:0019899 (enzyme binding)
GO:0042803 (protein homodimerization activity)
GO:0043295 (glutathione binding)
GO Biological Process GO:0006749 (glutathione metabolic process)
GO:0008152 (metabolic process)
GO:0018916 (nitrobenzene metabolic process)
GO:0042178 (xenobiotic catabolic process)
GO:1901687 (glutathione derivative biosynthetic process)
Wikipedia GSTM4

Target Cross References - Protein

canSAR Q03013
Human Protein Atlas ENSG00000168765
IntAct Q03013
Open Targets ENSG00000168765
PharmGKB PA29026
Reactome R-HSA-156590 (Glutathione conjugation.)
UniProt A8K765 Q03013 Q05465 Q32NC1 Q4JNT8 Q6FH87

Target Cross References - Domain

InterPro IPR003081 (GST_mu.)
IPR004045 (Glutathione_S-Trfase_N.)
IPR004046 (GST_C.)
IPR010987 (Glutathione-S-Trfase_C-like.)
IPR012336 (Thioredoxin-like_fold.)
Pfam PF02798 (GST_N)
PF14497 (GST_C_3)

Target Cross References - Structure

PDBe 4GTU
CREDO 4GTU
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