ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL2099
Target Type SINGLE PROTEIN
Preferred Name Prostate specific antigen
Synonyms APS | Gamma-seminoprotein | KLK3 | Kallikrein-3 | P-30 antigen | PSA | Prostate-specific antigen | Semenogelase | Seminin
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme > protease > serine protease > serine protease pa clan > serine protease s1a subfamily

Target Components

Component Description Relationship Accession
Prostate-specific antigen SINGLE PROTEIN P07288

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000142515
Ensembl ENSG00000142515
GO Cellular Component GO:0005576 (extracellular region)
GO Molecular Function GO:0004252 (serine-type endopeptidase activity)
GO Biological Process GO:0006508 (proteolysis)
GO:0016525 (negative regulation of angiogenesis)
Wikipedia Prostate-specific_antigen

Target Cross References - Protein

canSAR P07288
Human Protein Atlas ENSG00000142515
IntAct P07288
Guide to Pharmacology 2373 (kallikrein-related peptidase 3)
PharmGKB PA164741810
Reactome REACT_15380 (Diabetes pathways.)
UniProt P07288 Q16272 Q86TG8

Target Cross References - Domain

InterPro IPR001254 (Peptidase_S1_S6.)
IPR001314 (Peptidase_S1A.)
IPR009003 (Pept_cys/ser_Trypsin-like.)
IPR018114 (Peptidase_S1/S6_AS.)
Pfam PF00089 (Trypsin)

Target Cross References - Structure

PDBe 2ZCH 2ZCK 2ZCL
CREDO 2ZCH 2ZCK 2ZCL
spacer
spacer