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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL2049
Target Type SINGLE PROTEIN
Preferred Name Oxytocin receptor
Synonyms OT-R | OXTR | Oxytocin receptor
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > peptide receptor (family a gpcr) > short peptide receptor (family a gpcr) > vasopressin and oxytocin receptor

Target Components

Component Description Relationship Accession
Oxytocin receptor SINGLE PROTEIN P30559

Approved Drugs

ChEMBL ID Name Mechanism of Action References
CHEMBL395429 OXYTOCIN Oxytocin receptor agonist DailyMed ISBN

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000180914
Ensembl ENSG00000180914
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Molecular Function GO:0004990 (oxytocin receptor activity)
GO:0005000 (vasopressin receptor activity)
GO Biological Process GO:0006936 (muscle contraction)
GO:0007565 (female pregnancy)
GO:0007595 (lactation)
Wikipedia Oxytocin_receptor

Target Cross References - Protein

canSAR P30559
Human Protein Atlas ENSG00000180914
IUPHAR 369 (OT)
PharmGKB PA32858
Reactome REACT_14797 (Signaling by GPCR.)
UniProt P30559 Q15071

Target Cross References - Domain

InterPro IPR000276 (7TM_GPCR_Rhodpsn.)
IPR001817 (Vasoprsn_rcpt.)
IPR002062 (Oxytocn_rcpt.)
IPR017452 (GPCR_Rhodpsn_supfam.)
Pfam PF00001 (7tm_1)
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