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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1850
Preferred Name Dopamine D5 receptor
Synonyms D(1B) dopamine receptor | D(5) dopamine receptor | D1beta dopamine receptor | DRD1B | DRD1L2 | DRD5 | Dopamine D5 receptor
Organism Homo sapiens
Species Group No
Protein Target Classification
  • membrane receptor > family a g protein-coupled receptor > small molecule receptor (family a gpcr) > monoamine receptor > dopamine receptor

Target Components

Component Description Relationship Accession
D(1B) dopamine receptor SINGLE PROTEIN P21918

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL2096905 Dopamine receptor PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000169676
Ensembl ENSG00000169676
GO Cellular Component GO:0005887 (integral to plasma membrane)
GO Biological Process GO:0001963 (synaptic transmission, dopaminergic)
GO:0006874 (cellular calcium ion homeostasis)
GO:0007191 (activation of adenylate cyclase activity by dopamine receptor signaling pathway)
GO:0033861 (negative regulation of NAD(P)H oxidase activity)
GO:0060158 (activation of phospholipase C activity by dopamine receptor signaling pathway)
GO:0072593 (reactive oxygen species metabolic process)
Wikipedia Dopamine_receptor_D5

Target Cross References - Protein

canSAR P21918
Human Protein Atlas ENSG00000169676
Guide to Pharmacology 218 (D5)
PharmGKB PA148
Reactome REACT_14797 (Signaling by GPCR.)
UniProt B2R9S3 P21918 Q8NEQ8

Target Cross References - Domain

InterPro IPR000276 (7TM_GPCR_Rhodpsn.)
IPR000497 (Dopa_1B_rcpt.)
IPR000929 (Dopamine_rcpt.)
IPR017452 (GPCR_Rhodpsn_supfam.)
Pfam PF00001 (7tm_1)