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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1795192
Target Type SINGLE PROTEIN
Preferred Name Cyclin-dependent kinase 13
Synonyms CDC2-related protein kinase 5 | CDC2L | CDC2L5 | CDK13 | CHED | Cell division cycle 2-like protein kinase 5 | Cell division protein kinase 13 | Cholinesterase-related cell division controller | Cyclin-dependent kinase 13 | KIAA1791 | hCDK13
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Cyclin-dependent kinase 13 SINGLE PROTEIN Q14004

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3559691 Cyclin-dependent kinase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000065883
Ensembl ENSG00000065883
GO Cellular Component GO:0002945 (cyclin K-CDK13 complex)
GO:0005615 (extracellular space)
GO:0005634 (nucleus)
GO:0005654 (nucleoplasm)
GO:0005737 (cytoplasm)
GO:0005794 (Golgi apparatus)
GO:0016607 (nuclear speck)
GO:0019908 (nuclear cyclin-dependent protein kinase holoenzyme complex)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0008353 (RNA polymerase II carboxy-terminal domain kinase activity)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0030332 (cyclin binding)
GO:0044822 (poly(A) RNA binding)
GO Biological Process GO:0000380 (alternative mRNA splicing, via spliceosome)
GO:0006397 (mRNA processing)
GO:0006468 (protein phosphorylation)
GO:0007088 (regulation of mitotic nuclear division)
GO:0007275 (multicellular organism development)
GO:0008284 (positive regulation of cell proliferation)
GO:0008380 (RNA splicing)
GO:0016032 (viral process)
GO:0016310 (phosphorylation)
GO:0030097 (hemopoiesis)
GO:0070816 (phosphorylation of RNA polymerase II C-terminal domain)
Wikipedia CDC2L5

Target Cross References - Protein

canSAR Q14004
Human Protein Atlas ENSG00000065883
IntAct Q14004
Guide to Pharmacology 1966
Open Targets ENSG00000065883
PharmGKB PA26264
Pharos Q14004 (Tbio)
Reactome R-HSA-6796648 (TP53 Regulates Transcription of DNA Repair Genes.)
UniProt Q14004 Q53G78 Q6DKQ9 Q75MH4 Q75MH5 Q96JN4 Q9H4A0 Q9H4A1 Q9UDR4

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)

Target Cross References - Structure

PDBe 5EFQ
CREDO 5EFQ
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