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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1795191
Preferred Name Cyclin-dependent kinase 10
Synonyms CDK10 | Cell division protein kinase 10 | Cyclin-dependent kinase 10 | Serine/threonine-protein kinase PISSLRE
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Cyclin-dependent kinase 10 SINGLE PROTEIN Q15131

Target Relations

ChEMBL ID Pref Name Target Type
CHEMBL3559691 Cyclin-dependent kinase PROTEIN FAMILY

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000185324
Ensembl ENSG00000185324
GO Cellular Component GO:0005737 (cytoplasm)
GO:0005856 (cytoskeleton)
GO:0016592 (mediator complex)
GO:0036064 (ciliary basal body)
GO:0042995 (cell projection)
GO Molecular Function GO:0000166 (nucleotide binding)
GO:0004672 (protein kinase activity)
GO:0004674 (protein serine/threonine kinase activity)
GO:0004693 (cyclin-dependent protein serine/threonine kinase activity)
GO:0005515 (protein binding)
GO:0005524 (ATP binding)
GO:0016301 (kinase activity)
GO:0016740 (transferase activity)
GO:0097472 (cyclin-dependent protein kinase activity)
GO Biological Process GO:0006468 (protein phosphorylation)
GO:0007089 (traversing start control point of mitotic cell cycle)
GO:0008285 (negative regulation of cell proliferation)
GO:0016310 (phosphorylation)
GO:0018107 (peptidyl-threonine phosphorylation)
GO:0030030 (cell projection organization)
GO:0032956 (regulation of actin cytoskeleton organization)
GO:0043410 (positive regulation of MAPK cascade)
GO:1902018 (negative regulation of cilium assembly)
Wikipedia Cyclin-dependent_kinase_10

Target Cross References - Protein

canSAR Q15131
Human Protein Atlas ENSG00000185324
IntAct Q15131
Open Targets ENSG00000185324
PharmGKB PA26307
Pharos Q15131 (Tbio)
UniProt A8K370 A8K8I6 A8MXU6 B3KQJ3 B7Z420 D3DX82 D3DX83 Q0VGZ7 Q15130 Q15131 Q6PJC0

Target Cross References - Domain

InterPro IPR000719 (Prot_kinase_dom.)
IPR008271 (Ser/Thr_kinase_AS.)
IPR011009 (Kinase-like_dom_sf.)
IPR017441 (Protein_kinase_ATP_BS.)
Pfam PF00069 (Pkinase)