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ChEMBL

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ChEMBL Statistics
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Target Report Card

Target Name and Classification

Target ID CHEMBL1795185
Target Type SINGLE PROTEIN
Preferred Name Bromodomain testis-specific protein
Synonyms BRDT | Bromodomain testis-specific protein | CT9 | Cancer/testis antigen 9 | RING3-like protein
Organism Homo sapiens
Species Group No
Protein Target Classification
  • epigenetic regulator > reader > bromodomain

Target Components

Component Description Relationship Accession
Bromodomain testis-specific protein SINGLE PROTEIN Q58F21

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000137948
Ensembl ENSG00000137948
GO Cellular Component GO:0005634 (nucleus)
GO Molecular Function GO:0003713 (transcription coactivator activity)
GO:0042393 (histone binding)
GO:0070577 (lysine-acetylated histone binding)
GO Biological Process GO:0001207 (histone displacement)
GO:0006338 (chromatin remodeling)
GO:0006351 (transcription, DNA-templated)
GO:0006355 (regulation of transcription, DNA-templated)
GO:0006397 (mRNA processing)
GO:0007140 (male meiosis)
GO:0007141 (male meiosis I)
GO:0007283 (spermatogenesis)
GO:0008380 (RNA splicing)
GO:0016568 (chromatin modification)
GO:0030154 (cell differentiation)
GO:0043484 (regulation of RNA splicing)
GO:0051039 (positive regulation of transcription involved in meiotic cell cycle)
GO:0051321 (meiotic cell cycle)
Wikipedia BRDT

Target Cross References - Protein

canSAR Q58F21
Human Protein Atlas ENSG00000137948
IntAct Q58F21
Guide to Pharmacology 2729
Open Targets ENSG00000137948
PharmGKB PA25418
TIMBAL BRDT
UniProt A6NF68 B7Z811 B7Z890 B7ZAX7 D3DT32 O14789 Q05DQ4 Q58F21 Q6P5T1 Q7Z4A6 Q8IWI6

Target Cross References - Domain

InterPro IPR001487 (Bromodomain.)
IPR018359 (Bromodomain_CS.)
IPR027353 (NET_dom.)
IPR031354 (BRD4_CDT.)
Pfam PF00439 (Bromodomain)
PF17035 (BET)
PF17105 (BRD4_CDT)

Target Cross References - Structure

PDBe 2RFJ 4FLP 4KCX
CREDO 2RFJ 4FLP 4KCX
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