ChEMBL logo

ChEMBL

spacer
ChEMBL Statistics
  Loading Statistics...
spacer

Target Report Card

Target Name and Classification

Target ID CHEMBL1776
Target Type SINGLE PROTEIN
Preferred Name Inositol-1(or 4)-monophosphatase 2
Synonyms IMP 2 | IMP.18P | IMPA2 | IMPase 2 | Inositol monophosphatase 2 | Inositol-1(or 4)-monophosphatase 2 | Myo-inositol monophosphatase A2
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
Inositol monophosphatase 2 SINGLE PROTEIN O14732

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000141401
Ensembl ENSG00000141401
GO Cellular Component GO:0005737 (cytoplasm)
GO Molecular Function GO:0008934 (inositol-1(or 4)-monophosphatase activity)
GO:0042803 (protein homodimerization activity)
GO:0046872 (metal ion binding)
GO Biological Process GO:0007165 (signal transduction)
GO:0046855 (inositol phosphate dephosphorylation)
Wikipedia IMPA2

Target Cross References - Protein

canSAR O14732
Human Protein Atlas ENSG00000141401
IntAct O14732
Guide to Pharmacology 1464 (IMPase 2)
PharmGKB PA29861
UniProt B0YJ29 O14732 Q9UJT3

Target Cross References - Domain

InterPro IPR000760 (Inositol_monophosphatase.)
IPR020550 (Inositol_monophosphatase_CS.)
IPR020552 (Inositol_monoPase_Li-sen.)
IPR020583 (Inositol_monoP_metal-BS.)
Pfam PF00459 (Inositol_P)

Target Cross References - Structure

PDBe 2CZH 2CZI 2CZK 2DDK 2FVZ
CREDO 2CZH 2CZI 2CZK 2DDK 2FVZ
spacer
spacer