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Target Report Card

Target Name and Classification

Target ID CHEMBL1770047
Preferred Name Low affinity sodium-glucose cotransporter
Synonyms Low affinity sodium-glucose cotransporter | Na(+)/glucose cotransporter 3 | SAAT1 | SGLT2 | SLC5A4 | Sodium/glucose cotransporter 3 | Solute carrier family 5 member 4
Organism Homo sapiens
Species Group No
Protein Target Classification
  • transporter > electrochemical transporter > slc superfamily of solute carriers > slc05 family of sodium-dependent glucose transporters

Target Components

Component Description Relationship Accession
Low affinity sodium-glucose cotransporter SINGLE PROTEIN Q9NY91

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000100191
Ensembl ENSG00000100191
GO Cellular Component GO:0005887 (integral component of plasma membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO Molecular Function GO:0005215 (transporter activity)
GO:0005412 (glucose:sodium symporter activity)
GO:0015293 (symporter activity)
GO Biological Process GO:0006810 (transport)
GO:0006811 (ion transport)
GO:0006814 (sodium ion transport)
GO:0008643 (carbohydrate transport)
GO:0055085 (transmembrane transport)
GO:1904659 (glucose transmembrane transport)
Wikipedia SLC5A4

Target Cross References - Protein

Human Protein Atlas ENSG00000100191
IntAct Q9NY91
Open Targets ENSG00000100191
PharmGKB PA35904
Reactome R-HSA-189200 (Hexose transport.)
R-HSA-428808 (Na+-dependent glucose transporters.)
R-HSA-429593 (Inositol transporters.)
UniProt O15279 Q9NY91

Target Cross References - Domain

InterPro IPR001734 (Na/solute_symporter.)
IPR018212 (Na/solute_symporter_CS.)
Pfam PF00474 (SSF)