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Target Report Card

Target Name and Classification

Target ID CHEMBL1743317
Preferred Name UDP-glucuronosyltransferase 1-7
Synonyms GNT1 | UDP-glucuronosyltransferase 1-7 | UDP-glucuronosyltransferase 1-G | UDP-glucuronosyltransferase 1A7 | UDPGT 1-7 | UGT-1G | UGT1 | UGT1*7 | UGT1-07 | UGT1.7 | UGT1A7 | UGT1G
Organism Homo sapiens
Species Group No
Protein Target Classification
  • enzyme

Target Components

Component Description Relationship Accession
UDP-glucuronosyltransferase 1-7 SINGLE PROTEIN Q9HAW7

Target Associated Bioactivities

Target Associated Assays

Target Ligand Efficiencies

Target Associated Compound Properties

Target Cross References - Gene

Array Express ENSG00000244122
Ensembl ENSG00000244122
GO Cellular Component GO:0005783 (endoplasmic reticulum)
GO:0005789 (endoplasmic reticulum membrane)
GO:0016020 (membrane)
GO:0016021 (integral component of membrane)
GO:0043231 (intracellular membrane-bounded organelle)
GO Molecular Function GO:0001972 (retinoic acid binding)
GO:0004857 (enzyme inhibitor activity)
GO:0005080 (protein kinase C binding)
GO:0008144 (drug binding)
GO:0015020 (glucuronosyltransferase activity)
GO:0016740 (transferase activity)
GO:0016757 (transferase activity, transferring glycosyl groups)
GO:0016758 (transferase activity, transferring hexosyl groups)
GO:0019899 (enzyme binding)
GO:0042803 (protein homodimerization activity)
GO:0046982 (protein heterodimerization activity)
GO Biological Process GO:0006631 (fatty acid metabolic process)
GO:0007588 (excretion)
GO:0008152 (metabolic process)
GO:0009804 (coumarin metabolic process)
GO:0009813 (flavonoid biosynthetic process)
GO:0017144 (drug metabolic process)
GO:0042573 (retinoic acid metabolic process)
GO:0043086 (negative regulation of catalytic activity)
GO:0045922 (negative regulation of fatty acid metabolic process)
GO:0051552 (flavone metabolic process)
GO:0052695 (cellular glucuronidation)
GO:0052696 (flavonoid glucuronidation)
GO:0052697 (xenobiotic glucuronidation)
GO:1904224 (negative regulation of glucuronosyltransferase activity)
GO:2001030 (negative regulation of cellular glucuronidation)
Wikipedia UGT1A7_(gene)

Target Cross References - Protein

Human Protein Atlas ENSG00000244122
IntAct Q9HAW7
Open Targets ENSG00000244122
PharmGKB PA37182
Reactome R-HSA-156588 (Glucuronidation.)
UniProt B8K293 O00473 Q9HAW7

Target Cross References - Domain

InterPro IPR002213 (UDP_glucos_trans.)
Pfam PF00201 (UDPGT)